Wycombe Wanderers are the visitors on Saturday with the Chairboys looking to secure a victory that may yet see them go up automatically depending on other results.
But Chris Wilder will be equally determined for his men to end a solid season on a positive note and register what will be Northampton's 14th League Two victory at Sixfields in 2014/15.
22 games to date have also brought 2 draws and 7 defeats with the home side netting 37 goals, a total bettered only by Shrewsbury in the whole division.