Both sides are smarting from their respective results last weekend when they were both the victims of storming comebacks.
Oxford blew a two-goal lead against Morecambe to leave manager Chris Wilder urging his side to rediscover the 'winning mentality' that saw them promoted back into the Football League last season.
"We have to make sure we have that aggressive side to us."
The Cobblers of course were on the receiving end of an even bigger shock as Hereford scored four second-half goals to leave Sixfields with three points.
Boss Ian Sampson is worried about the fragile nature of his side.
“When we concede one we tend to concede two or three and it’s something we need to look at.”