Chris Wilder's side return to Sixfields after their midweek defeat at the hands of MK Dons, the prospect of promotion more than enough to keep spirits high despite missing the chance to host Chelsea in the next round of the FA Cup.
And, while the Cobblers aim to take three points from the Shrimps, in-form Bristol Rovers meet Plymouth Argyle and Portsmouth host Oxford United.
Previews of those matches can be seen on the official Football League website.