Northampton are confident that top scorer Adebayo Akinfenwa will return from his ankle injury while skipper Craig Hinton is back from suspension.
Luke Gutteridge serves the second game of his three-match ban while Andy Holt returns to the wing.
Shrewsbury will have an unchanged squad from their win over Lincoln.
But Nathan Elder's return from loan at AFC Wimbledon has been delayed after the striker suffered medial knee ligament damage.
Predict League Two results
Source: BBC Sport
Source: BBC Sport